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Raman Microscopy

The absorption and scattering of sunlight by matter is the reason why the sky and seas are blue, why plants are green, why rainbows have their brilliant colors and why sunglasses protect your eyes. Some of these everyday phenomena involve elastic scattering – scattering with no loss of energy...
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Correlative Microscopy in Materials Science

Correlative microscopy is not a single technique but a varied collection of techniques that share a common approach. By applying several different microscopy techniques, such as light microscopy and electron microscopy, to a single sample, scientists can study it at a much broader range of...
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Atomic Force Microscopy for Materials

Since its first introduction in the 1980s, atomic force microscopy (AFM) has become a widely-used technique for characterizing a variety of materials surface properties. AFM uses a cantilever with a sharp tip to detect the varying forces as the tip is scanned over a sample surface. Not only does...
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Familial Hypercholesterolaemia (FH)

Familial hypercholesterolaemia (FH) is the most common and serious form of inherited dyslipidaemia. FH is characterised by elevated plasma total cholesterol and low-density lipoprotein-cholesterol (LDL-C) levels from birth, frequently with other clinical signs such as tendon xanthomata. Increased...
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Focused Ion Beam-Scanning Electron Microscopy

With any kind of work, it helps to be able to see what you’re doing, but that can be a challenge when working at microscopic scales or below. By taking advantage of a system that combines two separate instruments – a focused ion beam (FIB) and a scanning electron microscope (SEM) –...
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Atom Probe Tomography

  Atom probe tomography (APT) offers the enticing prospect of being able to determine the identity and position of nearly every atom in a material, providing the ultimate in elemental analysis. The technique involves applying either ultra-fast voltage pulses or laser pulses to a...
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Wavelength-dispersive (X-ray) Spectroscopy

This EKB provides a clear and concise introduction to wavelength dispersive (X-ray) spectroscopy (WDS) as performed in electron microprobes and scanning electron microscopes. WDS has a wide range of potential applications, from its best-known use in earth sciences to analyze rocks and minerals, to...
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Life Science Microscopy Optics

Within the field of optical microscopy there are dozens of specialist techniques, all with their own particular characteristics. As a result using microscopes seriously for the first time can be a daunting task. This briefing provides newcomers to microscopy with an informative yet concise...
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