Electron Probe Microanalysis - new edition for 2018
EPMA is an analytical technique widely used for determining the elemental composition of solid specimens. In combining two complementary techniques, WDS and EDS, in a single microprobe, EPMA produces a powerful analytical instrument. This has a wide range of applications, from studying the latest...Read More
Super-resolution Microscopy
Super-resolution describes a range of techniques in fluorescence microscopy, which allow images to be taken in the 10–100nm resolution range. At the same time, these techniques retain the minimally invasive nature inherent to optical microscopy. Therefore, it is now possible to observe and to...Read More
Atomic Force Microscopy for Life Sciences
Atomic force microscopy (AFM) is becoming an increasingly popular tool in biomedical and biological studies. Using a cantilever with a sharp tip attached to the free end, AFM detects the varying forces as the tip is scanned over a sample surface. Not only does this allow it to build up an...Read More
Light-Sheet Fluorescence Microscopy
Fluorescence microscopy is a powerful imaging technology, from the subcellular domain to whole organisms. The outstanding image contrast achieved by specifically labeling the molecules, organelles or structures of interest makes it the most widely used contrasting method in biological imaging....Read More
Raman Microscopy
The absorption and scattering of sunlight by matter is the reason why the sky and seas are blue, why plants are green, why rainbows have their brilliant colors and why sunglasses protect your eyes. Some of these everyday phenomena involve elastic scattering – scattering with no loss of energy...Read More
Correlative Microscopy in Materials Science
Correlative microscopy is not a single technique but a varied collection of techniques that share a common approach. By applying several different microscopy techniques, such as light microscopy and electron microscopy, to a single sample, scientists can study it at a much broader range of...Read More
Atomic Force Microscopy for Materials
Since its first introduction in the 1980s, atomic force microscopy (AFM) has become a widely-used technique for characterizing a variety of materials surface properties. AFM uses a cantilever with a sharp tip to detect the varying forces as the tip is scanned over a sample surface. Not only does...Read More
Familial Hypercholesterolaemia (FH)
Familial hypercholesterolaemia (FH) is the most common and serious form of inherited dyslipidaemia. FH is characterised by elevated plasma total cholesterol and low-density lipoprotein-cholesterol (LDL-C) levels from birth, frequently with other clinical signs such as tendon xanthomata. Increased...Read More
Focused Ion Beam-Scanning Electron Microscopy
With any kind of work, it helps to be able to see what you’re doing, but that can be a challenge when working at microscopic scales or below. By taking advantage of a system that combines two separate instruments – a focused ion beam (FIB) and a scanning electron microscope (SEM) –...Read More
Atom Probe Tomography
Atom probe tomography (APT) offers the enticing prospect of being able to determine the identity and position of nearly every atom in a material, providing the ultimate in elemental analysis. The technique involves applying either ultra-fast voltage pulses or laser pulses to a...Read More
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