An Overview of 3D X-ray Microscopy
Scientists have long used X-rays to peer within solid objects, but the recent rise of X-ray microscopy (XRM) means they are now able to probe the secrets of matter in ever greater detail. Unlike most forms of microscopy, XRM can deliver high resolution and contrast in three dimensions, and can do...Read More
Dynamic Secondary Ion Mass Spectrometry
This new Essential Knowledge Briefing introduces dynamic SIMS, outlining its advantages over alternative surface analysis techniques, the major components of a typical dynamic SIMS instrument, and how and where it can be used. Four case studies provide examples of how SIMS is used in the real...Read More
Battery Research: Characterizing the Future
Many of our electronic devices are powered by rechargeable lithium-ion batteries. Use of these batteries could soon extend into many other areas, including transport through the ongoing development and adoption of electric vehicles. Scientists involved in developing and improving batteries require...Read More
Multiphoton Microscopy
With the ability to build up detailed 3D images of biological features at depths of up to 1mm without causing damage, multiphoton microscopy has proved adept at studying both biological samples and living organisms. As such, it is now a critical technique in life science disciplines such as...Read More
Electron Probe Microanalysis - new edition for 2018
EPMA is an analytical technique widely used for determining the elemental composition of solid specimens. In combining two complementary techniques, WDS and EDS, in a single microprobe, EPMA produces a powerful analytical instrument. This has a wide range of applications, from studying the latest...Read More
Atomic Force Microscopy for Life Sciences
Atomic force microscopy (AFM) is becoming an increasingly popular tool in biomedical and biological studies. Using a cantilever with a sharp tip attached to the free end, AFM detects the varying forces as the tip is scanned over a sample surface. Not only does this allow it to build up an...Read More
Light-Sheet Fluorescence Microscopy
Fluorescence microscopy is a powerful imaging technology, from the subcellular domain to whole organisms. The outstanding image contrast achieved by specifically labeling the molecules, organelles or structures of interest makes it the most widely used contrasting method in biological imaging....Read More
Raman Microscopy
The absorption and scattering of sunlight by matter is the reason why the sky and seas are blue, why plants are green, why rainbows have their brilliant colors and why sunglasses protect your eyes. Some of these everyday phenomena involve elastic scattering – scattering with no loss of energy...Read More
Atomic Force Microscopy for Materials
Since its first introduction in the 1980s, atomic force microscopy (AFM) has become a widely-used technique for characterizing a variety of materials surface properties. AFM uses a cantilever with a sharp tip to detect the varying forces as the tip is scanned over a sample surface. Not only does...Read More
Familial Hypercholesterolaemia (FH)
Familial hypercholesterolaemia (FH) is the most common and serious form of inherited dyslipidaemia. FH is characterised by elevated plasma total cholesterol and low-density lipoprotein-cholesterol (LDL-C) levels from birth, frequently with other clinical signs such as tendon xanthomata. Increased...Read More
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